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The latest wave of technological advancement is coming quickly, and it’s being led by Agentic AI (artificial intelligence). Agentic AI is different from older AI models because it has the ability to reason, act, and learn independently. Rather than being powered by simple rule-based programming, Agentic AI actually gets smarter and more efficient as time goes on.

Statista even estimates that the agentic AI market will be valued at $47.1 billion by 2032. This is just one of many Agentic AI stats that show us where the future of technology lies.

While the major players, such as Google, Apple, and Microsoft are investing in Agentic AI, a lot of this growth is being driven by relatively new startups. Here are 11 of the most creative startups that are building with agentic AI at the core of the organization. These companies aren’t just using simple frameworks or APIs, they’re creating fully autonomous systems.#

1. Aegis: Autonomous insurance claim appeal agent


Image via Aegis Homepage

Image via Aegis Homepage

Year founded: 2021

Aegis is streamlining insurance claims with AI agents that eliminate manual paperwork, long wait times, and endless back-and-forth. The company focuses on automating complex appeals and claim resolution workflows.

Aegis uses agentic AI to independently and autonomously navigate appealing denied insurance claims from start to finish. These agents make real-time decisions based on claim history, policy terms, and medical data, helping insurance providers resolve cases with a fraction of the manual labor. With contextual learning, they adapt to new claim types and insurer protocols over time, dramatically accelerating resolution while reducing overhead.

2. Approval AI: mortgage approval agent

Image via Approval AI


Image via Approval AI

Year founded: 2022

Approval AI is rethinking the home loan experience with autonomous systems that cut through red tape and decision bottlenecks. It specializes in helping consumers fully automate the mortgage shopping processing.

Approval AI’s system acts as a virtual middle man, sourcing available mortgages based on verified income and perceived risk, and negotiating on the consumer’s behalf. Then, following approval, you’ll be able to see all of the mortgages that you’ve been approved for at the best possible rates. 

On top of the cost savings, mortgage shopping can be a lengthy process with doing the same type of paperwork over and over. Approval AI’s system cuts the time investment substantially, since you won’t have to do the paperwork more than once. 

3. Galen AI: intelligent healthcare agent

Image via Galen AI


Image via Galen AI

Year founded: 2020

Galen AI provides proactive health guidance, using personal health data to deliver lifestyle and treatment suggestions. It’s built around the idea of a continuous-care AI partner that’s always looking out for you.

Galen AI uses user health data collected from devices like Fitbits and Apple Watches, as well as EMR records in order to spot patterns, flag concerns, and offer personalized interventions before symptoms escalate. 

Unlike reactive healthcare bots, Galen attempts to work out the best course of action proactively using the available data, adapt based on user goals, and initiates check-ins. That’s why Galen AI is more of a digital wellness coach than a chatbot. This application of Agentic AI in healthcare has huge potential, considering that the healthcare market is estimated to reach almost $45 trillion by 2032.

4. Ellipsis Health: listening AI for patient emotional health

Image via Ellipsis Health


Image via Ellipsis Health

Year founded: 2017

Ellipsis Health is changing the world of mental health care and follow-up by embedding intelligent voice analysis into healthcare workflows. Its flagship product is “Sage,” an AI-driven listener.

Sage acts as a conversational agent that manages check-ins, listens for emotional distress, and flags mental health concerns autonomously. It does more than just analyze tone or speech, it uses agentic reasoning to assess how a patient is really doing and escalate to a human provider when necessary. 

They claim that using Sage has helped mental health providers reduce up to 60% of administrative tasks, work that can really weigh a clinic down. By reducing clinician burden and improving access, Sage is paving the way for Agentic AI tools in emotional wellness.

5. Hyperbots: bookkeeping automation agent

Image via Hyperbots


Image via Hyperbots

Year founded: 2021

Hyperbots is reinventing how businesses manage their finances with a series of intelligent agents that handle repetitive accounting and finance tasks that are subject to human error. You can think of Hyperbots as your autonomous finance team.

Hyperbots uses Agentic AI to automatically invoice clients, manage payments, reconcile books, and more. These agents act without the need of human oversight, continuously monitoring accounts, correcting anomalies, and adapting workflows based on client needs. Over time, they can even learn preferred reporting formats and compliance nuances unique to each business.

6. ThriveAI: autonomous product team assistant

Imagea via ThriveAI


Imagea via ThriveAI

Year founded: 2022

ThriveAI gives product teams a powerful advantage by offering product management teams with  an autonomous agent that can analyze, prioritize, and synthesize useful data at scale.

ThriveAI’s agent is an always-on project manager embedded in your organization’s digital network that digests user feedback, watches metrics, and independently suggests roadmap adjustments. 

Removing the waiting period for manual effort, it will proactively notify teams about changing user needs in the company or industry, or potential churn. Its full autonomy enables organizations to achieve real-time alignment between its customer base’s sentiment and the state of their product.

7. Moments Lab: autonomous video production assistant

Image via Moments Lab


Image via Moments Lab

Year founded: 2021

Moments Lab brings next-gen automation to video production by giving media companies a centralized dashboard where they can store and work with their raw footage.

The company’s Agentic AI system (called MXT) can review unlimited hours of footage, making a searchable, filterable database of your content, automatically edit and share clips from live events, and more, totally hands off. These agents are trained not just on editing mechanics but on emotional and narrative arcs, allowing them to make creative decisions without human input in the form of templates or prompts.

Moments Lab primarily focuses on providing footage management with media companies, though their use cases don’t stop there.

8. Decidr: AI-driven HR agent

Image via Decidr


Image via Decidr

Year founded: 2020

Decidr is rethinking talent management with Agentic AI systems that enhance hiring, learning, and internal mobility across large organizations, through its suite of Agentic AI agents.

Decidr’s recruitment agent doesn’t just filter resumes. It acts on real-time business needs, matches potential candidates to open jobs based on behavioral signals, and coordinates job interviews and/or follow ups. Because it uses Agentic AI, it can operate across silos, working together with the systems your organization uses like Slack, email, LMS tools, and other databases. This optimizes every stage of the hiring process, limiting the need for manual oversight.

9. Poolside: your software development team’s new co-engineer

Image via Poolside AI


Image via Poolside AI

Year founded: 2023

Poolside is building a new class of large language models made specifically for software development teams. Their goal is to make autonomous code generation secure, scalable, and production-ready.

Poolside’s models don’t just respond to prompts, they act as end-to-end agents for development tasks. These agents can help plan features, write/revise code, and even identify performance or security risks independently. Designed with collaboration in mind, they integrate within your own environment to make your software development a breeze, no matter where you’re working. 

Being installed directly within the software development team’s environment also helps keep things secure, reducing the risk of outside attack.

10. Qodo: autonomous code debugging agents 

Image via Qodo


Image via Qodo

Year founded: 2022

Qodo is on a mission to eliminate stumbling blocks in writing, testing, and releasing code by using AI agents that think and act like real developers.

Qodo’s uses agentic AI agents to proactively write and revise code, monitor live systems for regressions, and trace and debug through codebases. All of this is done 100% autonomously, without the need for manual oversight. 

These agents can write, edit, and test code across Python, JavaScript, C#, Rust, PHP, Kotlin, and SQL. As for supported AI models, the platform supports models from Anthropic, OpenAI, Deepseek, and Gemini. 

11. Devin: 100% autonomous software engineer

Image via Devin AI


Image via Devin AI

Year founded: 2024

Devin has captured global attention by introducing what many consider the world’s first fully autonomous software developer.

Devin can independently plan, code, debug, and even deploy software projects with minimal input. From a simple message on Slack, Devin will launch into action, figuring out how to tackle the requested project and immediately following through on the plan.

What makes Devin truly agentic is its ability to self-direct — breaking down goals, asking follow-up questions when needed, and recruiting additional AI agents to finish sub-tasks. With Devin, you’re not just getting a software assistant; it’s a fully capable autonomous software engineer.

See how Agentic AI is transforming all industries

These 11 startups are showing that building an AI platform with the ability to autonomously reason and act is no longer a distant dream. Across many different industries, these Agentic AI startups are pushing the boundaries of efficiency in the world of automation. 

From healthcare to HR, and everywhere in between, these companies are using Agentic AI to unlock speed, scale, and strategic decision-making like never before with systems that do more than just assist humans, but autonomously manage complex workflows from start to finish.

At Atera, we’re bringing this same level of autonomy to IT management. With our Robin and AI Copilot, IT teams are able to automate ticket resolutions, proactively patch systems, summarize remote sessions, and a whole lot more. 

Atera AI Copilot is transforming IT work.

If you’d like to see how Agentic AI is changing the IT world for yourself, you can get a free 30-day trial of Atera. You’ll have 30 days to try out our industry-leading IT management platform, and to see how using Copilot as your new autonomous IT assistant can save you up to 13 hours per week.

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